Department of Health
John J. Dreyzehner, MD, MPH, Commissioner

At room temperature, ammonia is a colorless gas with a very pungent odor. This odor is familiar to many people because ammonia is used commonly in cleaning products and smelling salts.

Ammonia gas can be dissolved in water. When this happens, it is called liquid ammonia or aqueous ammonia. People most often encounter ammonia as a liquid chemical in cleaning products. Once exposed to open air, liquid ammonia quickly turns back into a gas. Ammonia is also commonly used in fertilizers for farm crops, lawns, and plants.

For industrial and agricultural purposes, ammonia is often shipped as a liquefied, compressed gas. This is commonly called anhydrous ammonia as it has no water.

Ammonia occurs naturally in the atmosphere.  Ammonia is formed in the body during the decomposition of organic materials. Bacteria found in the intestines can also produce ammonia.

Ammonia has a very strong odor. If ammonia cannot be smelled, it is probably not enough to be harmful.  If you can smell ammonia, then health effects are possible with eye, nose, or throat irritation being the most common effects. Leave an area that smells like ammonia for fresh air. Ventilate the area to clear the ammonia.

If you get ammonia in your eyes or if ammonia is swallowed, then call the
Tennessee Poison Center at 1-800-222-1222.

Ammonia occurs naturally in the environment. Ammonia does not last very long in the environment. It is rapidly taken up by plants, bacteria, and animals. Ammonia serves as a nutrient for plants and bacteria. It is an important source of nitrogen needed by plants and animals. Ammonia does not build up in the food chain.

For industrial and agricultural purposes, ammonia is often shipped as a liquefied, compressed gas. Ammonia is used in commercial refrigeration. Ammonia is applied directly into soil on farm fields.

Since ammonia occurs naturally in the environment, we are regularly exposed to low levels of it in the air, soil, animals, and water. Harmful exposures to ammonia could come from cleaning products or commercial applications.

People may be exposed to ammonia gas outdoors in the air from leaks and spills at production plants or storage facilities. It could leak from pipelines, tank trucks, railcars, ships, and barges that transport ammonia. Higher levels of ammonia in the air may occur when fertilizer with ammonia compounds is applied to farm fields. Farmers, cattle ranchers, and people who raise other types of livestock or poultry can be exposed to ammonia from decaying manure. Some manufacturing processes also use ammonia.

People may be exposed to ammonia indoors while using household products that contain ammonia such as cleaning solutions, window cleaners, floor waxes, and smelling salts. Remember to ventilate rooms when you clean with ammonia and dilute it as recommended on the label. Never mix ammonia with bleach. Keep chemical cleaners out of reach of children to prevent exposure and poisoning.

Ammonia can also be released into the household air when pets urinate on rugs and when litter boxes are not changed often enough.

Some people could be exposed to ammonia at a job site. The Occupational Safety and Health Administration (OSHA) has a workplace standard for ammonia. If you might be exposed to lots of ammonia on the job, you may need special hazardous chemical training and personal protective equipment.

A chemical-free home is part of a healthy home. There are several alternative cleaning products that can be used in place of ammonia. Mixing natural products such as water with vinegar makes a good cleaner. Also, consider using baking soda. Other non-toxic cleaners, such as citrus-based cleaners, are widely available in retail stores.

Ammonia can enter the body if you breathe ammonia gas or if you swallow water or food containing ammonium salts. Most of the ammonia that enters our body is from food or water that rapidly changes into other substances that will not harm us. You can breathe in ammonia when using cleaning products. Most ammonia that enters the body leaves in urine within a couple of days.

Larger amounts of ammonia may enter the body of people exposed from an ammonia spills or gas leak. There is no antidote for acute ammonia poisoning, but ammonia's effects can be treated. Persons who have experienced serious signs and symptoms may need to be hospitalized. Most people recover.

Ammonia is not hazardous to health at concentrations typically found in the environment. At higher concentrations ammonia can be harmful. The most common health effect is irritation to the eyes, nose, or throat.

• If swallowed, ammonia will cause pain and burning in the throat and stomach.
• If touched, ammonia can cause irritation or burns to the eyes or skin.
• If breathed in, ammonia can irritate the respiratory tract and can cause coughing, wheezing,
  and shortness of breath. Inhalation of ammonia can also cause nose and throat irritation.
• People can smell the pungent odor of ammonia in air at about 5 parts of ammonia in
  a million parts of air (ppm).
• According to World Health Organization (WHO), continuous exposure to 25 parts per million (ppm) of ammonia in the air does not result in a significant increase in blood levels of ammonia in the body.
• According to the Occupational Safety and Health Administration (OSHA), the least amount of ammonia
  which is found to be irritating to the eyes, nose and throat of the most sensitive individuals
  is 50 parts per million (ppm).
• There is no evidence that ammonia causes cancer.
• Frostbite can occur with exposure to anhydrous ammonia.
• Exposure to very high concentrations of ammonia gas can cause pulmonary edema, upper respiratory irritation, tearing of the eyes, increased pulse rate, and increased blood pressure.
• Death has been reported after an exposure to 10,000 ppm for an unknown duration.
• There is no evidence that exposure to the levels of ammonia found in the environment
  causes birth defects or other developmental effects.
• Because ammonia is a respiratory tract irritant, persons who are hyper reactive to other
  respiratory irritants or are asthmatic, may be more susceptible to the inhalation of ammonia.

If you suspect an ammonia spill, call the Tennessee Department of Environment and Conservation’s environmental hotline number at 1-888-891-TDEC (8332).

Questions about ammonia and your health are best asked to your medical provider. For general questions about ammonia, contact the Tennessee Department of Health’s Environmental Epidemiology Program at eep.health@tn.gov or 615-741-7247 or 1-800-404-3006.

Tennessee Poison Center (1-800-222-1222)
www.mc.vanderbilt.edu/root/vumc.php?site=poisoncenter

Agency for Toxic Substances and Disease Registry
www.atsdr.cdc.gov/substances/toxsubstance.asp?toxid=2

TOXNET
toxnet.nlm.nih.gov/

Haz-Map
hazmap.nlm.nih.gov/

Medline Plus
www.nlm.nih.gov/medlineplus/